WAPP
Chemistry Lab9 min read

How a LIMS works: one sample from request to signed test report

Maksim

Maksim

Founder / CTO

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How a LIMS works: one sample from request to signed test report

A customer calls: the oil sample from their compressor was tested two weeks ago, the report says the viscosity is out of spec, and they want to know which instrument measured it and whether it was in calibration that day. In a lab that runs on spreadsheets, answering takes an afternoon of digging through folders. In a lab with a LIMS, it takes one click on the sample card. That is, in short, how a LIMS works: every result stays linked to the sample, method, analyst and instrument behind it.

A laboratory information management system (LIMS) is the software that tracks every sample from the moment a customer asks for a test to the signed test report — and keeps a record of who did what, when, and with which equipment. Below is how that works in practice, using the LIMS we build at WAPP as the example.

What a LIMS does in a testing lab

A LIMS replaces the sample log, the instrument calibration spreadsheet, the folder of method documents and the report template in Word with one system where these records are linked. The links are the point: a result is tied to a sample, the sample to a method, the measurement to an instrument, and the instrument to its calibration record.

For a lab working under ISO/IEC 17025, these links are what an assessor checks. They want to see that a result can be traced back to a qualified analyst, a valid method and a calibrated instrument.

A sample's path through the LIMS

A sample goes through seven stages on its way from the customer's request to a signed test report. At each one, the LIMS adds its own record to the sample card.

Each step adds its own record to the sample card, so the final report can be traced back to every decision behind it

The customer request opens the job

Work starts with a request from a customer: what needs testing, which parameters, how urgent. The LIMS keeps a customer directory, so the contact person, contract details and history of previous tests are already there. The request becomes the starting point for one or several samples.

Registration gives the sample an ID, a QR code and the data the report needs

The receptionist or analyst registers the sample when it arrives. The LIMS assigns a unique ID and generates a QR code for the label, so the bottle or container can be scanned at any later step instead of reading a handwritten number.

At registration the system records what the report will need later:

  • the customer and the request;
  • sampling date and sampling report number;
  • test type: product quality control, testing under a program, or certification testing;
  • sample details — for oil analysis, for example, the lubricant grade, equipment operating hours and top-up volume;
  • planned test date and an urgency flag;
  • storage conditions such as temperature and humidity.

The sample status becomes "registered". From now on, every change to the card is written to the audit trail.

The sample list shows status, customer and method on every card, so the lab manager sees the day's workload at a glance. Screenshots: WAPP LIMS with demo data

The method sets which parameters are measured

The method defines how the test is done and which parameters are measured. The LIMS keeps a method catalog with versions, so everyone works from the current revision, and the sample card shows which version was used. Each method lists its parameters (indicators) with units and the equipment it requires.

This removes a common source of errors: an analyst using an outdated method sheet printed months ago.

Instrument calibration is checked before the measurement

When the analyst starts work, the sample moves to "in progress". The analyst selects the instruments used for the measurement, and the LIMS shows each one's calibration status: valid, expiring soon, or expired.

Calibration intervals and due dates live in the equipment register, with a calendar that shows what is due this month. The lab manager sees expiring calibrations before they become a finding, not after.

Each instrument goes into the report with its certificate and expiry date. The ICP spectrometer is flagged as expiring soon three weeks before the deadline

The equipment register also separates two kinds of records that spreadsheets often mix up:

  • measuring instruments — what the lab measured with; these go into the report with their calibration details;
  • sampled objects — the engine, gearbox or tank the sample was taken from; these go into the sample description.

The test report is assembled from records the system already holds

Results are entered against the method's parameters, with units already set. The LIMS assembles the test report from the records it already holds: customer, sample description, method, conditions, results, and the measuring instruments with their calibration data. That last block is what ISO/IEC 17025 clause 7.8.2 asks a test report to contain about the equipment used.

Report templates are configured once per report type, so analysts do not reformat a Word file for every sample. How to make sure a report has everything it needs is covered in our article on the contents of a test report.

The analyst and the reviewer sign, each in their role

Before a report goes to the customer, the people responsible sign it: the analyst who performed the test and the person who reviews and approves it. The LIMS records who signed, in which role and when. Roles define who can register samples, enter results, approve reports or change reference data, so each action is done by someone allowed to do it.

After approval the sample is "completed". If a sample cannot be tested — wrong container, insufficient volume, damaged seal — it is marked "rejected", and that decision is recorded in the audit trail too.

Results sit next to their limits and test methods, and each signature carries the person's role and the exact time

The audit trail answers "who changed this?"

Every change in the system — a corrected result, a new calibration date, a reassigned analyst — is written to the audit trail with the user, time and previous value. The traceability view shows the full history of a sample on one screen.

The audit trail answers who changed what and when — including the water content correction made before the report was signed

This is what answers the customer call from the beginning of this article: open the sample, see the instrument, open the instrument, see its calibration on the test date.

Spreadsheets vs a LIMS: what changes day to day

TaskSpreadsheets and paperLIMS
Find a sampleSearch the log by date or customerScan the QR code or search by ID
Check an instrument's calibrationOpen a separate file, hope it is currentStatus shown when the instrument is selected
Prepare a test reportCopy data into a Word templateReport assembled from existing records
Answer "who changed this result?"Usually impossibleAudit trail with user, time and old value
Prepare for an assessmentCollect records from several foldersRecords are already linked to each sample

What to check when choosing a LIMS

A LIMS only pays off if analysts actually use it. Before choosing a system, check four things:

  1. Does registering a sample take less time than writing it in the log? If not, staff will keep the log.
  2. Can it hold the fields your samples actually need — for oil analysis, environmental testing or food testing they differ a lot.
  3. Does the test report come out in the format your customers and assessors expect, without manual edits?
  4. Who can change the configuration — methods, templates, roles — without calling the vendor?

Why analysts quietly go back to spreadsheets, and how to avoid it, is covered in Why lab staff bypass LIMS.

How WAPP builds LIMS for testing labs

WAPP builds LIMS around the lab's real workflow: the sample card holds the fields your samples need, report templates match your current documents, and the system runs on your own server if data cannot leave the company. For small labs of up to about 10 people there is a free base version — details are on the LIMS page. An example of a larger project is the SPEKTROKHIM case: a platform for interlaboratory proficiency testing.

Frequently asked questions about how a LIMS works

Key takeaways

A LIMS follows each sample from request to signed report and links every result to a method, an analyst and a calibrated instrument. The value is not in replacing paper as such, but in answering "where did this number come from?" in seconds. When choosing a system, start with how long it takes to register a sample and whether the report comes out the way your customers expect.

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